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Polyphenolic profile, antioxidant properties and antimicrobial activity of grape skin extracts of 14 Vitis vinifera varieties grown in Dalmatia (Croatia).

Polyphenolic profile, antioxidant properties and antimicrobial activity of grape skin extracts of 14 Vitis vinifera varieties grown in Dalmatia (Croatia).










No.Divisions/Titles for AbstractDetails

1Abstract TitlePolyphenolic profile, antioxidant properties and antimicrobial activity of grape skin extracts of 14 Vitis vinifera varieties grown in Dalmatia (Croatia).


2Abstract Source Food Chemistry, 119, 715-723.


3Abstract Author(s)Katalinić, V., Možina, S. S., Skroza, D., Generalić, I., Abramovič, H., Miloš, M., Ljubenkov, I., Piskernik, S., Pezo, I., Terpinc, P. & Boban, M.


4Article Affiliation

a Faculty of Chemistry and Technology, University of Split, Teslina 10, 21000 Split, Croatia

b Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1111 Ljubljana, Slovenia

c SMS – Nutrition Development Center, Kurtovići bb, 21231 Klis, Croatia

d Institute of Adriatic Crops and Carst Reclamation, Put Duilova 11, 21000 Split, Croatia

e School of Medicine, University of Split, Šoltanska 2, 21000 Split, Croatia.



5AbstractThe aim of the present study was to determine polyphenolic composition, related antioxidative and antimicrobial properties of grape skin extracts from 14 grape varieties (seven white and seven red grape) grown in Dalmatia (Croatia). The content of total phenols, flavonoids, catechins, flavanols and individual polyphenols ((+)-catechin, (−)-epicatechin, epicatechin gallate, procyanidin B1 and procyanidin B2, quercetin glucoside, resveratrol monomers, piceid and astringin) was variety dependent. Antioxidant properties were determined as DPPH radical-scavenging ability (IC50), ferric reducing/antioxidant power (FRAP), Fe2+-chelating activity (IC50), and using β-carotene bleaching assay. The high antioxidant capacity of all extracts, both red and white, has been observed and related to the relative amounts of polyphenolic compounds with good antioxidant properties. The antimicrobial activity was screened by broth microdilution test using Gram-positive (Staphylococcus aureus, Bacillus cereus) and Gram-negative bacteria (Escherichia coli O157:H7, Salmonella Infantis, Campylobacter coli). It was confirmed against all tested organisms. Minimum inhibitory concentrations (MICs), were found in the range 0.014–0.59 mg of gallic acid equivalents (GAE)/ml, with lower MICs of white cultivars, especially against Campylobacter and Salmonella.


6Summaryantioxidative and antimicrobial properties of grape skin extracts from 14 grape varieties studied.


7Article Published DateMarch 2010.


8Study TypeInvitro.

9SubstancesGrape skin.

10Diseasescancer, microbial infections of Gram-positive (Staphylococcus aureus, Bacillus cereus) and Gram-negative bacteria (Escherichia coli O157:H7, Salmonella Infantis, Campylobacter coli).


11Pharmacological Actionsantioxidant , antimicrobial.


12Linkhttps://goo.gl/j3ATqC








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