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Effects of oral bovine colostrum supplementation on serum insulin-like growth factor-i levels.

Effects of oral bovine colostrum supplementation on serum insulin-like growth factor-i levels.









No. Divisions/Titles for Abstract Details

1 Abstract Title Effects of oral bovine colostrum supplementation on serum insulin-like growth factor-i levels.


2 Abstract Source Nutrition, 18, 566-567.


3 Abstract Author(s) Kuipers, H., Van Breda, E., Verlaan, G. & Smeets, R.


4 Article Affiliation a Maastricht University, Maastricht, The Netherlands
b Numico Research, Wageningen, The Netherlands.


5 Abstract OBJECTIVES:
We investigated whether supplementation with 60 g/d of bovine colostrum affects blood levels of insulin-like growth factor-I (IGF-I) and IGF binding protein-3 in relation to doping testing. Nine endurance-trained men ingested 60 g/d of bovine colostrum for 4 wk.
METHODS:
Blood and urine were sampled before starting supplementation. After 4 wk urine and blood samples were taken after an overnight fast and 2 h after ingestion of the last portion to study possible acute effects.
RESULTS:
Blood IGF-I levels before supplementation were (mean ± standard deviation) 31 ± 13 nM/L, and no acute effects were observed after 4 wk of supplementation (33 ± 9 nM/L). Levels of IGF-binding protein-3 were 136 ± 11 nM/L before supplementation and 135 ± 16 nM/L after 4 wk of supplementation. Two hours after ingestion of the last portion, the level of IGF binding protein-3 was 131 ± 19 nM/L, which was not different from baseline values. Drug testing in a laboratory accredited by the International Olympic Committee did not show any forbidden substance before or after 4 wk of supplementation.
CONCLUSIONS:
Daily supplementation with 60 g of bovine colostrum for 4 wk does not change blood IGF-I or IGF binding protein-3 levels and does not elicit positive results on drug tests.


6 Summary Daily supplementation with 60 g of bovine colostrum for 4 wk does not change blood IGF-I or IGF binding protein-3 levels and does not elicit positive results on drug tests (doping testing ).


7 Article Published Date  July–August 2002.


8 Study Type clinical.


9 Substances colostrum.


10 Diseases effects of colostrum on doping testing.


11 Pharmacological Actions effect of colostrum on  insulin-like growth factor-I (IGF-I) and IGF binding protein-3.


12 Link https://goo.gl/V9Uu1M








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