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Effects of a Dietary Supplement with Barley Sprout Extract on Blood Cholesterol Metabolism.

Effects of a Dietary Supplement with Barley Sprout Extract on Blood Cholesterol Metabolism.

No. Divisions/Titles for Abstract Details

1 Abstract Title Effects of a Dietary Supplement with Barley Sprout Extract on Blood Cholesterol Metabolism.

2 Abstract Source Evidence-Based Complementary and Alternative Medicine, Volume 2015, Article ID 473056, 7 pages.

3 Abstract Author(s) Byun, A. R., Chun, H., Lee, J., Lee, S. W., Lee, H. S. & Shim, K. W.

4 Article Affiliation Department of Family Medicine, Ewha Woman’s University Mokdong Hospital, Ewha Woman’s University School of Medicine, Seoul, Republic of Korea.

5 Abstract Objective. Barley sprout (Hordeum vulgare L.) contains 4.97% fat, 52.6% polysaccharide(a carbohydrate that can be decomposed by hydrolysis into two or more molecules of monosaccharides), and 34.1% protein along with a variety of vitamins, minerals, and polyphenolic compounds. Hexacosanol is one such compound from the barley leaf that might improve cholesterol metabolism by decreasing cholesterol synthesis. Method. Therefore, this study was conducted to investigate the effects of barley sprout extract on serum(The clear liquid that can be separated from clotted blood) lipid metabolism in healthy volunteers(A person used to study normal physiology and behavior or who does not have a condition being studied in a particular protocol, used to compare with subjects who do have the condition) (𝑛 = 51). Subjects were randomly divided into two groups: one group consumed a single capsule of barley leaf extract daily (𝑛 = 25, 42.48 ± 13.58 years) and the other consumed placebo(an inert or innocuous substance used especially in controlled experiments testing the efficacy of another substance) capsules (𝑛 = 26, 40.54 ± 11.1 years) for 12 weeks. Results. After 12 weeks, total cholesterol and low-density lipoprotein- (LDL-) cholesterol were not lower in the barley sprout extract group compared to the placebo group (𝑝 = 0.415 and 𝑝 = 0.351, resp.) and no differences in clinical or laboratory findings were observed between both groups. Conclusion. Our study failed to show significant lipid-lowering effects of barley sprout extract, possibly due to dosage, duration of therapy, and small sample size(The number of subjects in a clinical trial). Despite our nonsignificant findings, barley sprout has a possibility as a functional health food; therefore future research is needed.

6 Summary The findings of this clinical trial indicate that barley sprout extract, as a functional health food, cannot replace lipid-lowering drugs, such as statins or fenofibrates. However, the positive effects that have been reported repeatedly in diverse laboratory studies, including animal models. Barley sprout extract may improve lipid metabolism and lower cardiovascular disease risk in people with borderline cholesterol levels, although it may not replace current drug therapies.

7 Article Published Date 2015 May 25.

8 Study Type Clinical.

9 Substances Barley sprout extract.

10 Diseases Blood cholesterol metabolism.

11 Pharmacological Actions Cardioprotective.

12 Link

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